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Chemical Reactions

Our equipment and experience enable us to carry out a large number of chemical reactions for API development and production.

But every synthesis requires it's own production strategy to achieve the optimal result.  We can help you develop your own production strategy, under confidential disclosure agreements which allow you to share your knowledge and set the stage for a close collaboration from an early start of our project, help you save time and money on API development.

Here are some of the reactions we have run in large scale recently:

  • Organometallic, i.e. Grignard, Reformatsky
  • Silylorganic reactions
  • Condensations, i.e. Aldol, Claisen-Schmidt, Knoevenagel, Mannich
  • Olefin formation, i.e. Wittig
  • Acylations, i.e. Friedel-Craft, Houben-Hoesch, Vielsmeier-Haak,
  • Enamine reactions, i.e. acylation, alkylation, reduction
  • Reductions, i.e. catalytic, hydride, Clemmensen
  • Reductive reactions, i.e. acetylation, alkylation, amination
  • Ring formation, i.e. Claisen, Caroll, Favorskii, Nazarov
  • Phosphorylations
  • Reactions with strong acids/base, acid chlorides, anhydrides, thionyl chlorides
  • Multi-phase reactions, i.e. Phase -transfer catalysis