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Why Choose DuPont Dimethyl Sulfate?

Unmatched Product Stewardship

DuPont offers training and support to ensure our products are handled safely. We make available to customers a variety of safety videotapes, seminars, and site safety surveys.

Dependable Shipments

Our shipping record is excellent. Your order will be delivered by personnel trained to handle DMS properly and safely.

What is Dimethyl Sulfate?

Dimethyl sulfate (DMS), CAS number [77-78-1], is a strong methylating agent used to make surfactants, fabric softeners, water treatment chemicals, pesticides, drugs, dyes, and photographic chemicals. Although used mainly for methylating, it can be used, under certain conditions, as a sulfonation agent, catalyst, solvent, and stabilizer (see "Uses").

Dimethyl sulfate, (CH3)2SO4 , is a clear, water-white liquid with a high boiling point and a high vapor density. This chemical is highly toxic and has no characteristic odor or warning property. Both the liquid and vapor cause severe burns to human tissue.

This chemical requires extreme care in storage and handling. Although it is highly toxic, dimethyl sulfate can be handled safely if proper precautions are taken.

Do not handle or use dimethyl sulfate until you have read and understand the latest DuPont DMS Material Safety Data Sheet (MSDS) .

The vapor pressure of dimethyl sulfate at 20°C (68°F) will give a saturated vapor concentration in air of 710 parts per million by volume. Higher temperatures will give correspondingly higher concentrations of vapor in air. Because of the toxic nature of dimethyl sulfate vapor, reactions should be carried out in closed equipment. Laboratory work should be done in ventilated hoods, and process areas should be outdoors or in well ventilated areas. The lack of distinct odor and water-like appearance of DMS makes spill detection difficult.