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Disposable injector pen uses new low-friction grade of DuPont™ Delrin® for healthcare applications

Geneva, Switzerland, October 18, 2011

Ypsomed AG (Burgdorf, Switzerland) has specified a new, ultra low-friction grade of DuPont™ Delrin® acetal resin for a key component of its UnoPen™, a disposable, variable-dose injector pen for insulin and other therapies. The DuPont material, which is supplied with full regulatory compliance for use in healthcare applications, is used to mold the pen's dose dial sleeve. Its low-friction behavior facilitates use of the pen by diabetes patients who are required to administer daily injections of insulin either by themselves or with the help of a health care professional. Further attributes of Delrin® in the application include its mechanical properties and the compatibility of the material with laser marking when using a masterbatch.

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A new, ultra low-friction grade of DuPont™ Delrin® acetal resin, which is supplied with full regulatory compliance for use in healthcare applications, has been specified by Ypsomed AG (Burgdorf, Switzerland) for a key component of its UnoPen™ disposable injector pen.

Photo: courtesy of Ypsomed

The UnoPen™ from Ypsomed AG, a leading independent developer and manufacturer of injection systems, is a state-of-the-art disposable pen designed for the manual injection and delivery of insulin or other drugs from a pre-filled glass cartridge. A principal feature of the device is its ease-of-use based on a well-proven 'dial and inject' handling concept, in which the dose dial sleeve — the component molded from Delrin®  and located between the housing and the piston rod - plays a key role. It is used by the patient to set the required dose of insulin to be injected and interacts mechanically with the piston rod to dispense the required dosage.

"The friction properties of the material used for the dose dial sleeve are fundamental to the pen's ease of use. If friction between the parts of the pen is kept to its minimum, then the patient will need a minimum of force to dose or inject the drug," explains Stefan Burren, manager product development at Ypsomed. "We tested many polymers that are currently available on the market for this component, but none fulfilled the requirements as well as the DuPont material."

The new Delrin® grade has been modified for exceptional low friction performance and is suitable for high volume manufacture. It has been specifically developed for parts requiring high precision molding in the healthcare industry and is supplied with the relevant regulatory compliance (FDA and EU food compliance, production according to GMP standards, testing against USP Class VI and ISO 10993 5+11). Further attributes of the new grade leading to its specification for the dose dial sleeve include its compatibility with laser marking, by use of an appropriate masterbatch, for indication of the dose settings. As with other grades from the Delrin® family, the material also exhibits outstanding properties in terms of strength and stiffness, permitting the snap-fit assembly of the component, as well as ensuring reliable and durable mechanical performance in use. 

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The Ypsomed Group is a leading, independent developer and manufacturer of injection systems for self care and a proven diabetes specialist with over 25 years of experience. Amongst its products, the company manufactures injection systems and pen needles for treating diabetes, growth disorders, infertility and other therapeutic areas and is further trading a complete product portfolio of diabetes care products such as insulin pumps and supplies and blood glucose monitoring systems. The Ypsomed Group is headquartered in Burgdorf, Switzerland. It has several production sites in Switzerland, as well as a large international sales and distribution network with presence in over 50 countries. The group currently employs around 1,100 staff.

DuPont Performance Polymers is committed to working with customers throughout the world to develop new products, components and systems that help reduce dependence on fossil fuels and protect people and the environment. With more than 40 manufacturing, development and research centers throughout the world, DuPont Performance Polymers uses the industry's broadest portfolio of plastics, elastomers, renewably sourced polymers, filaments and high-performance parts and shapes to deliver cost-effective solutions to customers in aerospace, automotive, consumer, electrical, electronic, industrial, sporting goods and other diversified industries.

DuPont is one of the first companies to publicly establish environmental goals more than 20 years ago — has broadened its sustainability commitments beyond internal footprint reduction to include market-driven targets for both revenue and research and development investment. The goals are tied directly to business growth, specifically to the development of safer and environmentally improved new products for key global markets.

DuPont (NYSE: DD) has been bringing world-class science and engineering to the global marketplace in the form of innovative products, materials, and services since 1802. The company believes that by collaborating with customers, governments, NGOs, and thought leaders we can help find solutions to such global challenges as providing enough healthy food for people everywhere, decreasing dependence on fossil fuels, and protecting life and the environment. For additional information about DuPont and its commitment to inclusive innovation, please visit www.dupont.com.


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